|Affiliation||Riken Center for Sustainable Resource Science|
|Keyword||base metal catalysis, C-H bond activation|
|Institute||The Chemical Society of Japan; The Society of Synthetic Organic Chemistry, Japan; The Japanese Society for Process Chemistry|
I plan to investigate the hybrid radical/organometallic reactivity of first row transition metals such as iron, manganese, cobalt, or nickel for the selective functionalization of C(sp3)-H bonds. Based on a previous discovery of a hybrid dual reactivity of organoiron, which behaves both as a radical to cleave a C(sp3)-H bond under mild conditions and as an organometal to create a new C–C or C–heteroatom bond, I plan to develop an efficient hybrid catalytic system for the functionalization of both simple hydrocarbons and of complex functional molecules.
- "Iron-Catalyzed Synthesis of Indenones through Cyclization of Carboxamides with Alkynes"
*Laurean Ilies, Yasin Arslanoglu, Tatsuaki Matsubara, *Eiichi Nakamura
Asian J. Org. Chem.,2018, 7, 1327-1329
- "Silylation of Aryl Halides with Monoorganosilanes Activated by Lithium Alkoxide"
Takumi Yoshida, *Laurean Ilies, *Eiichi Nakamura
Org. Lett.,2018, 20, 2844–2847
- "Synthesis of Esomeprazole and Related Proton Pump Inhibitors through Iron-Catalyzed Enantioselective Sulfoxidation"
*Shigenobu Nishiguchi, Takuhiro Izumi, Takayoshi Kouno, Junpei Sukegawa, *Laurean Ilies, *Eiichi Nakamura
ACS Catal.,2018, 8, 9738−9743
- "Iron-Catalyzed Directed Alkylation of Carboxamides with Olefins via a Carbometalation Pathway"
*Laurean Ilies, Yi Zhou, Haotian Yang, Tatsuaki Matsubara, Rui Shang, *Eiichi Nakamura
ACS Catal.,2018, 8, 11478–11482
- The 13th International Conference on Cutting-Edge Organic Chemistry in Asia (ICCEOCA-13)
"C-H Activation with Base Metals", 招待講演
11/1/2018-11/4/2018, Chulabhorn Research Institute (Bangkok), Thailand
- The 4th International Symposium on C-H Activation (ISCHA-4)
"Iron-Catalyzed C–H Bond Activation", 招待講演
8/30/2018-9/2/2019, Keio University (Hiyoshi), Japan
- The 1st Sino-Japanese Symposium on Catalysis for Precision Synthesis
"Iron Likes Single Electron Transfer", 招待講演
5/27/2018-5/30/2018, Shanghai Institute of Organic Chemistry (Shanghai), China
- 「Lectureship Award」
贈呈元：Asian CORE Program/Advanced Research Network