Grant-in-Aid for Scientific Research on Innovative Areas FY2017-2021Hybrid Catalysis

Hirofumi Ueda » Japanese

Affiliation Tohoku University, Graduate School of Pharmaceutical Sciences
Position Lecturer
Contact Email
HP http://www.pharm.tohoku.ac.jp/~seizou/index.html
Speciality Synthetic Organic Chemistry
Keyword Total Synthesis, Alkaloids, Domino Reaction
Institute The Pharmaceutical Society of Japan, The Society of Synthetic Organic Chemistry, Japan

Abstract

Our group focuses on natural alkaloids possessing complex and unique skeletons as new drug candidates. In order to establish efficient and divergent synthesis of these complex compounds, we are engaged on development of domino-type synthetic transformations and tandem catalysis, which are able to minimize numbers of steps, reagents and operation time. Finally, we are also interesting new hybrid catalysis developed in this research group and willingly utilize the method in our natural product synthesis.

Achievement

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Original papers

  • "Double Functionalization of Styrenes by Cu-mediated Assisted Tandem Catalysis"
    Kawauchi, D.; Ueda, H.; *Tokuyama, H.
    Eur. J. Org. Chem., 2/15/2019, 15, 2056-2060