Achievements

Name: Keiji Maruoka

Original papers

  • "Construction of a Quaternary Carbon Center by Catalytic Asymmetric Alkylation of 3-Arylpiperidin-2-ones under Phase-Transfer Conditions"
    Inukai, T.; Kano, T.; Maruoka, K.
    Angew. Chem. Int. Ed., 2/2020, 59(6), 2211-2214
  • "Asymmetric Synthesis of Chiral Sulfoximines via the S-Arylation of Sulfinamides
"
    Aota, Y.; Kano, T.; Maruoka, K.
    J. Am. Chem. Soc., 12/2019, 141(49), 19263-19268
  • "Efficient Synthesis of Cyclic Sulfoximines from N-Propargylsulfinamides through Sulfur–Carbon Bond Formation"
    Aota, Y.; Maeda, Y.; Kano, T.; Maruoka, K.
    Chem.–Eur. J., 11/2019, 25(69), 15755-15758
  • "Asymmetric Synthesis of Chiral Sulfoximines through the S-Alkylation of Sulfinamides"
    Aota, Y.; Kano, T.; Maruoka, K.
    Angew. Chem. Int. Ed., 10/2019, 58(49), 17661-17665
  • "Synthesis of Phenylcyclopropane-Based Secondary Amine Catalysts and Their Applications in Enamine Catalysis"
    Takeshima, A. Kano, T.; Maruoka, K.
    Org. Lett., 10/2019, 21(19), 8071-8074
  • "Scalable Synthesis of a Chiral Selenium π-Acid Catalyst and Its Use in Enantioselective Iminolactonization of β,γ-Unsaturated Amides"
    Otsuka, Y.; Shimazaki, Y.; Nagaoka, H.; Maruoka, K.; Hashimoto, H.
    Synlett, 9/2019, 30(14), 1679-1682
  • "Synthesis of α-Quaternary Aldehydes via a Stereoselective Semi-Pinacol Rearrangement of Optically Active Epoxy Alcohols
"
    Hirama, N.; Sakamoto, R.; Maruoka, K.
    Asian J. Org. Chem., 8/2019, 8(8), 1390-1393
  • "Asymmetric Synthesis of Chiral 1,4-Enynes through Organocatalytic Alkenylation of Propargyl Alcohols with Trialkenylboroxines
"
    Bai, J.-F.; Yasumoto, K.; Kano, T.; Maruoka, K.
    Angew. Chem. Int. Ed., 6/2019, 58(26), 8898-8901
  • "One-Pot Synthesis of Less Accessible N-Boc-Propargylic Amines Through BF3-Catalyzed Alkynylation and Allylation Using Boronic Esters"
    Yasumoto, K.; Kano, T.; Maruoka, K.
    Org. Lett., 5/2019, 21(9), 3214-3217
  • "Design of New Amino Tf- Amide Organocatalysts: Environmentally Benign Approach to Asymmetric Aldol Synthesis
"
    Lee, H.-J.; Arumugam, N.; Almansour, A. I.; Kumar, R. S.; *Maruoka, K.
    Synlett, 3/2019, 30, 401-404
  • "Generation of Alkyl Radicals from Alkylsilyl Peroxides and Their Applications to C-N or C-O Bond Formations
"
    Sakurai, S.; Kato, T.; Sakamoto, R.; *Maruoka, K.
    Tetrahedron, 1/2019, 75, 172-179
  • "Design of New Amino Tf- Amide Organocatalysts: Environmentally Benign Approach to Asymmetric Aldol Synthesis"
    Lee, H.-J.; Arumugam, N.; Almansour, A. I.; Kumar, R. S.; Maruoka, K.
    Synlett, 3/2019, 30(4), 401-404
  • "Iodine(III)-Catalyzed Electrophilic Nitration of Phenols via Non-Brønsted Acidic NO2+ Generation
"
    Juarez-Ornelas, K. A.; Jimenez-Halla, J. O. C.; Kato, T.; *Solorio-Alvarado, C. R.; *Maruoka, K.
    Org. Lett., 3/2019, 21, 1315-1319
  • "Enantioselective Alkynylation of Isatin Derivatives Using a Chiral Phase-TransferTransition- Metal Hybrid Catalyst System
"
    Paria, S.; Lee, H.-J.; *Maruoka, K.
    ACS Catal., 3/2019, 9, 2395-2399
  • "Benzimidazole Tethered Pyrrolo[3,4-b]quinoline with Broad-spectrum Activity Against Fungal Pathogens
"
    Villa, P.; *Arumugam, N.; Almansour, A. I.; Kumar, R. S.; Mahalingam, S. M.; Maruoka, K.; *Thangamani, S.
    Bioorg. Med. Chem. Lett., 3/2019, 29, 729-733
  • "Generation of Alkyl Radicals from Alkylsilyl Peroxides and Their Applications to C- N or C- O Bond Formations"
    Sakurai, S.; Kato, T.; Sakamoto, R.; Maruoka, K.
    Tetrahedron, 1/2019, 75(2), 172-179
  • "Design of Efficient Chiral Bifunctional Phase-Transfer Catalysts Possessing an Amino Functionality for Asymmetric Aminations
"
    Paria, S.; Kang, Q.-K.; Hatanaka, M.; *Maruoka, K.
    ACS Catal., 1/2019, 9, 78-82
  • "Practical Synthesis of Four Different Pseudoenantiomeric Organocatalysts with Both Cis- and Trans-Substituted 1,2-Cis-cyclohexanediamine Structures from a Common Intermediate"
    
 Lee, H.-J.; Arumugam, N.; Almansour, A. I.; Kumar, R. S.; *Maruoka, K.
    Tetrahedoron, 9/2018, 74, 5263-5269
  • "BF3-Catalyzed Synthesis of Cyclic Carbamates from Boc-Protected Aminals and Alkynes
"
    *Kano, T.; Yasumoto, K.; *Maruoka, K.
    Asian J. Org. Chem., 8/2018, 7, 1575-1578
  • "The Radical Acylarylation of N-Arylacrylamides with Aliphatic Aldehydes Using the Photolysis of Hypervalent Iodine(III) Reagents
"
    Sakamoto, R.; Hirama, N.; *Maruoka, K.
    Org. Biomol. Chem., 7/2018, 16, 5412-5415
  • "Enantioselective Alkylation of N-Arylhydrazones Derived from α-Keto Esters and Isatin Derivatives through Asymmetric Phase-Transfer Catalysis
"
    Kang, Q.-K.; Selvakumar, S.; Arumugam, N.; Almansour, A. I.; Kumar, R. S.; *Maruoka, K.
    Chemistry–Asian J., 7/2018, 13, 1780-1783
  • "Synthesis of 1-Aminoindenes through Aza-Prins-Type Cyclization"
    
 Bai, J.-F.; Yasumoto, K.; *Kano, T.; *Maruoka, K.
    Chemistry–Eur. J., 7/2018, 24, 10320-10323
  • "Transition-Metal-Free Direct C-H Silylation of Electron-Deficient Heteroarenes with Hydrosilanes via a Radical Mechanism
"
    Sakamoto, R.; Nguyen, B.-N.; *Maruoka, K.
    Asian J. Org. Chem., 7/2018, 7, 1085-1088
  • "Phase-transfer-catalysed Asymmetric Synthesis of 2,2-Disubstituted 1,4-Benzoxazin-3-ones
"
    Pawliczek, M.; Shimazaki, Y.; Kimura, H.; Oberg, K. M.; Zakpur, S.; Hashimoto, T.; *Maruoka, K.
    Chem. Commun., 6/2018, 54, 7078-7080
  • "Indanol-Based Chiral Organoiodine Catalysts for Enantioselective Hydrative Dearomatization
"
    Hashimoto, T.; Shimazaki, Y.; Omatsu, Y.; *Maruoka, K.
    Angew. Chem. Int. Ed., 6/2018, 57, 7200-7204
  • "A Synthetic Route to Sodium α-Aminoalkanesulfinates and Their Application in the Generation of α-Aminoalkyl Radicals for Radical Addition Reactions"
    Sakamoto, R.; Yoshii, T.; Takada, H.; *Maruoka, K.
    Org. Lett., 4/2018, 20, 2080-2083
  • "Catalyst-Controlled Diastereoselectivity Reversal in the Formation of Dihydropyrans"
    
*Kano, T.; Maruyama, H.; Homma, C.; *Maruoka, K.
    Chem. Commun., 4/2018, 54, 3496-3499
  • "Copper- Catalyzed C(sp) - C(sp3) Coupling of Terminal Alkynes with Alkylsilyl Peroxides via a Radical Mechanism"
    Sakamoto, R.; Kato, T.; Maruoka, K.
    Org. Lett. , 3/2018, 20(5), 1400-1403
  • "Alkylative Kinetic Resolution of Vicinal Diols under Phase- Transfer Conditions: A Chiral Ammonium Borinate Catalysis
"
    Pawliczek, M.; Hashimoto, T. Maruoka, K.
    Chem. Sci., 2/2018, 9(5), 1231-1235
  • "Chiral Amine-Catalyzed Asymmetric Conjugate Addition of Aldehydes to α-Phenylselenoenones as Formal Z-Allylating Agents"
    
Kano, T.; Maruyama, H.; Homma, C.; Maruoka, K.
    Chem. Commun. , 1/2018, 54(2), 176-179
  • "Asymmetric Synthesis of Less Accessible α-Tertiary Amines from Alkynyl Z-Ketimines"
    
Kano, T.; Aota, Y.; Maruoka, K.
    Angew. Chem. Int. Ed. , 12/2017, 56(51), 16293-16296
  • "Synthesis of Chiral Tritylpyrrolidine Derivatives and Their Application to Asymmetric Benzoyloxylation
"
    Shimogaki, M.; Maruyama, H.; Tsuji, S.; Homma, C.; Kano, T.; Maruoka, K.
    J. Org. Chem. , 12/2017, 82(23), 12928-12932
  • "The Direct C- H Difluoromethylation of Heteroarenes Based on the Photolysis of Hypervalent Iodine(III) Reagents That Contain Difluoroacetoxy Ligands"
    Sakamoto, R.; Kashiwagi, H.; Maruoka, K.
    Org. Lett. , 10/2017, 19(19), 5126-5129
  • "Hypervalent Iodine(III) Catalyzed Radical Hydroacylation of Chiral Alkylidenemalonates with Aliphatic Aldehydes under Photolysis
"
    Selvakumar, S.; Kang, Q.-K..; Arumugam, N.; Almansour, A. I.; Kumar, R. S.; Maruoka, K.
    Tetrahedron, 10/2017, 73(40), 5841-5846
  • "Practical Synthesis of Two Different Pseudoenantiomeric Organocatalysts with cis-Cyclohexanediamine Structure from a Common Chiral Source
"
    Lee, H.-J.; Moteki, S. A.; Arumugam, N.; Almansour, A. I.; Kumar, R. S.; Liu, Y.; Maruoka, K.
    Asian J. Org. Chem. , 9/2017, 6(9), 1226-1230
  • "Catalyst-Controlled, Enantioselective and Diastereodivergent Conjugate Addition of Aldehydes to Electron-Deficient Olefins"
    
Kan, S. B. J.; Maruyama, H.; Akakura, M.; Kano, T.; Maruoka, K.
    Angew. Chem. Int. Ed., 7/2017, 56(32), 9487-9491
  • "In- Situ Generation of N- Boc- Protected Alkenyl Imines: Controlling the E/Z Geometry of Alkenyl Moieties in the Mukaiyama- Mannich Reaction
"
    J.-F. Bai, J.-F.; Sasagawa, H.; Yurino, T.; Kano, T.; Maruoka, K.
    Chem. Commun. , 7/2017, 53(58), 8203-8206
  • "Alkylsilyl Peroxides as Alkylating Agents in the Copper-Catalyzed Selective Mono-N-Alkylation of Primary Amides and Arylamines"
    Sakamoto, R.; Sakurai, S.; Maruoka, K.
    Chem. Eur. J., 7/2017, 23(38), 9030-9033

Review

  • 「The Design of Environmentally-Benign, High-Performance Organocatalysts for Asymmetric Catalysis」 Sakamoto, R.; Maruoka, K. , J. Synth. Org. Chem., Jpn. , 75, 1141-1149, 11, 11/2017
  • 「Practical Synthesis of Both Enantiomeric Amino Acid, Mannich, and Aldol Derivatives by Asymmetric Organocatalysis
」 Liu, Y.; Arumugam, N.; Almansour, A. I.; Kumar, R. S.; Maruoka, K., Chem. Rec. , 17, 1059-1069, 10, 10/2017

Conference

  • 5th International Symposium on Middle Molecular Strategy (ISMMS)
    "Practical Synthesis of Artificial Amino Acids and Peptides", 基調講演
    Maruoka, K.
    11/2019-11/2019, Awaji, Japan
  • The 19th Tateshina Conference
    "Design of High-Performance Organocatalysts with Privileged Structures for Selective Organic Synthesis", 基調講演
    Maruoka, K.
    11/2019-11/2019, Chino, Japan
  • Israel-Japan Conference
    "Design of Organoradical Catalysts for Selective Organic Synthesis", 招待講演
    Maruoka, K.
    11/2019-11/2019, Haifa, Israel
  • The 6th Tishler-Omura Symposium
    "Design of Chiral High-Performance Organocatalysts for Asymmetric Catalysis", 招待講演
    Maruoka, K.
    10/2019-10/2019, Tokyo, Japan
  • The 8th Japanese-Sino Symposium on Organic Chemistry for Young Scientists
    "Design of New, High-Performance Organoradical Catalysts for Selective Organic Synthesis", 基調講演
    Maruoka, K.
    9/2019-9/2019, Kyoto, Japan
  • 2019 Designing Molecules Workshop and Conference
    "Design of High-Performance Organocatalysts with Privileged Structures for Asymmetric Catalysis", 招待講演
    Maruoka, K.
    8/2019-8/2019, Kansas, U. S. A.
  • 31st International Symposium on Chirality
    "Design of New, High-Performance Organocatalysts with Privileged Structures for Asymmetric Catalysis", 招待講演
    Maruoka, K.
    7/2019-7/2019, Bordeaux, France
  • Symposium on Molecular Chirality 2019
    "Design of Chiral High-Performance Organocatalysts for Asymmetric Catalysis", 招待講演
    Maruoka, K.
    6/2019-6/2019, Kanazawa, Japan
  • 6th Japan-UK Symposium on Asymmetric Synthesis
    "Design of New, High-Performance Organoradical Catalysts with Privileged Structures for Asymmetric Catalysis", 招待講演
    Keiji Maruoka
    11/28/2018-11/29/2018, Fukuoka, Japan
  • The 13th International Symposium on Organic Reactions (ISOR-13)
    "Design of New, High-Performance Organoradical Catalysts with Privileged Structures for Asymmetric Catalysis", 招待講演
    Keiji Maruoka
    11/21/2018-11/24/2018, Hsinchu, Taiwan
  • The Organic Chemistry Day in Pavia
    "Asymmetric Enamine Catalysis with Nitroso and Related Compounds Catalyzed by High-Performance Organocatalysts", 招待講演
    Keiji Maruoka
    10/11/2018-10/11/2018, Pavia, Italy
  • Boehringer-Ingelheim Lectureship [2]
    "Design of Bifunctional Organocatalysts by Experimental and Computational Studies, and Design of New Organoradical Catalysts with Privileged Structure", 招待講演
    Keiji Maruoka
    8/11/2018-8/11/2018, Boston, U. S. A.
  • Boehringer-Ingelheim Lectureship [1]
    "Asymmetric Phase-Transfer Catalysis: Basic Design of Maruoka Catalyst® and the Industrial Application", 招待講演
    Keiji Maruoka
    8/10/2018-8/10/2018, Boston, U. S. A.
  • The Second Japanese-Spanish Symposium on Organic Synthesis
    "Advantage of Chiral Amino Organocatalysts over Proline in Asymmetric Enamine Catalysis: A Good Harmony with Water", 招待講演
    Keiji Maruoka
    5/28/2018-5/29/2018, Kyoto, Japan
  • Departmental Organic Seminar
    "Design of High-Performance Organocatalysts with Privileged Structures for Asymmetric Catalysis", 招待講演
    Maruoka, K.
    3/13/2018-3/13/2018, Alicante, Spain
  • 8th International Collaborative and Cooperative Chemistry Symposium (8th ICCCS)
    "Design of High-Performance Organocatalysts for Catalytic Asymmetric Synthesis", 招待講演
    Maruoka, K.
    12/18/2017-12/19/2017, Hyderabad, India
  • Singapore Japan Germany Trilateral Symposium on Precision Synthesis & Catalysis
    "Practical Synthesis of Four Different, Bifunctional Organocatalysts for Asymmetric Catalysis", 招待講演
    Maruoka, K.
    11/20/2017-11/21/2017, Singapore, Singapore
  • Second International Conference on Organic Chemistry at GDUT
    "Design of High-Performance Organocatalysts for Catalytic Asymmetric Synthesis ", 招待講演
    Maruoka, K.
    11/11/2017-11/12/2017, Guangzhou, China
  • 8th Pacific Symposium on Radical Chemistry
    "New Strategy of Generating Carbon Radicals for Organic Synthesis", 招待講演
    Maruoka, K.
    7/18/2017-7/22/2017, Brisbane, Australia
  • 4th Elemento-Organic Chemistry Symposium – Asymmetric Synthesis: The Methods and Applications
    "Design of High-Performance Organocatalysts with Privileged Structures for Asymmetric Catalysis", 招待講演
    Maruoka, K.
    7/14/2017-7/15/2017, Tianjin, China
  • 2nd International Conference on Hydrogen Atom Transfer (iCHAT 2017)
    "New Strategy of Generating Acyl Radicals for Organic Synthesis", 招待講演
    Maruoka, K.
    7/2/2017-7/6/2017, Rome, Italy

Domestic Conference

  • 学術講演会
    "Design of High-Performance Organocatalysts for Asymmetric Catalysis and Radical Chemistry", 招待講演
    Maruoka, K.
    2/2020-2/2020, 沖縄
  • リトリートシンポジウム
    "高性能ハイブリッド触媒系を活用する高選択的ドミノ反応の開発", 口頭発表
    丸岡啓二
    1/31/2018-1/31/2018, 蒲郡
  • 第1回公開シンポジウム
    "高性能ハイブリッド触媒系を活用する高選択的ドミノ反応の開発", 口頭発表
    丸岡啓二
    1/30/2018-1/30/2018, 名古屋
  • 特別講演会
    "高性能有機触媒を活用する触媒的不斉合成の最前線", 招待講演
    丸岡啓二
    11/30/2017-11/30/2017, 岡山
  • キックオフシンポジウム
    "高性能ハイブリッド触媒系を活用する高選択的ドミノ反応の開発", 口頭発表
    丸岡啓二
    9/14/2017-9/14/2017, 東京

Media

  • Synfacts
    「Indanol-Based Chiral Organoiodine Catalysts for Enantioselective Hydrative Dearomatization」
    Hashimoto, T.; Shimazaki, Y.; Omatsu, Y.; *Maruoka, K. , 4/2018